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Case‐control analyses: Geneopardy!
Author(s) -
Jorgenson Eric,
Liu Xin,
Witte John S.
Publication year - 2005
Publication title -
genetic epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.301
H-Index - 98
eISSN - 1098-2272
pISSN - 0741-0395
DOI - 10.1002/gepi.20114
Subject(s) - control (management) , statistics , biology , geography , mathematics , computer science , artificial intelligence
The case‐control analyses group focused on a diverse set of questions, including study design, power, and analysis of case‐control studies. Papers on study design examined various case‐selection strategies, as well as ways to combine information from family‐ and population‐based case‐control data. The power of various approaches to case‐control analyses was compared in several papers, while two papers chose to apply specific methods to analyzing the data. Two groups examined haplotype‐related issues, including resolving unphased haplotypes and comparing haplotype‐ and single‐nucleotide polymorphism‐based methods for analyzing data. Finally, one group examined the optimal number of markers for the genomic control approach to population stratification. Genet. Epidemiol . 29(Suppl. 1):S86–S90, 2005. © 2005 Wiley‐Liss, Inc.