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Tree‐Based Linkage and Association Analyses of Asthma
Author(s) -
Zhang Heping,
Tsai Chin-Pei,
Yu Chang-Yung,
Bonney George
Publication year - 2001
Publication title -
genetic epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.301
H-Index - 98
eISSN - 1098-2272
pISSN - 0741-0395
DOI - 10.1002/gepi.2001.21.s1.s317
Subject(s) - linkage (software) , association mapping , genetic linkage , association (psychology) , genetic association , biology , genetics , chromosome , data set , tree (set theory) , complete linkage , evolutionary biology , computational biology , statistics , genotype , mathematics , gene , psychology , combinatorics , single nucleotide polymorphism , psychotherapist
Tree‐based linkage analyses and association studies are introduced and applied for two data sets on asthma from Genetic Analysis Workshop 12. Consistent and strong evidence of linkage and association to markers on chromosomes 1 and 11 is revealed. Linkage to chromosome 16 in one data set and association with D6S276 in the other data set are also detected. © 2001 Wiley‐Liss, Inc.