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A genetic analysis of common disease data
Author(s) -
Cantor Rita M.
Publication year - 1995
Publication title -
genetic epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.301
H-Index - 98
eISSN - 1098-2272
pISSN - 0741-0395
DOI - 10.1002/gepi.1370120634
Subject(s) - linkage (software) , quantitative trait locus , genetic linkage , biology , disease , genetics , regression analysis , computational biology , regression , gene , statistics , mathematics , medicine
Simulated common disease data have been analyzed to identify a model of disease expression that involves the complex interaction of quantitative traits controlled by major genes and an environmental factor. Correlation and multiple regression analyses in conjunction with quantitative sib‐pair linkage analyses revealed a portion of the model involved. © 1995 Wiley‐Liss, Inc.