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Sequential imputation and multipoint linkage analysis
Author(s) -
Kong Augustine,
Cox Nancy,
Frigge Mike,
Irwin Mark
Publication year - 1993
Publication title -
genetic epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.301
H-Index - 98
eISSN - 1098-2272
pISSN - 0741-0395
DOI - 10.1002/gepi.1370100626
Subject(s) - imputation (statistics) , linkage (software) , statistics , computational biology , biology , genetics , computer science , mathematics , missing data , gene
A novel Monte Carlo method for linkage analyses involving large pedigrees and many polymorphic loci is introduced. Issues related to the efficiency of the method are discussed. © 1993 Wiley‐Liss, Inc.
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