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Toronto‐Rochester depression study of 116 HLA‐typed kindreds
Author(s) -
Stancer H. C.,
Weitkamp L. R.,
Persad E.,
Flood C.,
Jorna T.,
Guttormsen S. A.,
Yagnow R. L.
Publication year - 1989
Publication title -
genetic epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.301
H-Index - 98
eISSN - 1098-2272
pISSN - 0741-0395
DOI - 10.1002/gepi.1370060134
Subject(s) - pedigree chart , depression (economics) , family history , human leukocyte antigen , psychiatry , psychology , family studies , clinical psychology , medicine , genetics , gerontology , gene , biology , immunology , antigen , economics , macroeconomics
The Toronto‐Rochester Depression study consisted of 116 pedigrees ascertained for multiple cases of major affective disorders. Among the 857 psychiatrically evaluated family members, of whom more than 85% were given a structured interview, 363 had major affective disorder by Research Diagnostic Criteria and 385 had no history of psychological aberration. HLA region genes were typed in 804 of these persons.