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Estimation of segregation and ascertainment probabilities by discarding the single probands
Author(s) -
Li C. C.,
Chakravarti Aravinda,
Halloran Susan L.,
Rao D. C.
Publication year - 1987
Publication title -
genetic epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.301
H-Index - 98
eISSN - 1098-2272
pISSN - 0741-0395
DOI - 10.1002/gepi.1370040303
Subject(s) - proband , statistics , estimation , econometrics , mathematics , computer science , genetics , biology , mutation , economics , gene , management
The first portion of this communication reiterates the method of discarding single probands for studying the segregation ratio under incomplete ascertainment. The organization of the algebra leads to the second portion, in which the “self‐contained” subsets are constructed with respect to both the segregation ratio and the ascertainment ratio. These subsets make a more detailed study of segregation and ascertainment possible.