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The recurrence risks for isolated cases with incompletely penetrant X‐linked conditions
Author(s) -
Rogatko A.,
Rao D. C.
Publication year - 1986
Publication title -
genetic epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.301
H-Index - 98
eISSN - 1098-2272
pISSN - 0741-0395
DOI - 10.1002/gepi.1370030508
Subject(s) - penetrance , proband , penetrant (biochemical) , genetics , medicine , biology , mutation , gene , microbiology and biotechnology , phenotype
The recurrence risks for an X‐linked disease with incomplete penetrance are evaluated for a sib given that an isolated proband (male or female) is affected. The derived formulae are applied to the X‐linked form of Alport and fragile X syndromes.
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