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The information content of phase‐known matings for ordering genetic loci
Author(s) -
Timothy Bishop D.,
Rao D. C.
Publication year - 1985
Publication title -
genetic epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.301
H-Index - 98
eISSN - 1098-2272
pISSN - 0741-0395
DOI - 10.1002/gepi.1370020404
Subject(s) - pairwise comparison , linkage (software) , lod score , set (abstract data type) , genetics , content (measure theory) , genetic linkage , interpretation (philosophy) , quantitative trait locus , biology , data set , statistics , mathematics , computer science , gene , gene mapping , chromosome , mathematical analysis , programming language
This analysis evaluates the amount of linkage information that can be obtained for ordering three loci. The information contents of data collected on three independent pairwise samples of two loci, and data obtained jointly from three loci in a single set of individuals are compared. The level of support of the maximum likelihood order and the interpretation of that support are also examined.