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Genetic analysis workshop III: Simple methods for accurate gene mapping with multipoint data
Author(s) -
Risch N.
Publication year - 1985
Publication title -
genetic epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.301
H-Index - 98
eISSN - 1098-2272
pISSN - 0741-0395
DOI - 10.1002/gepi.1370020221
Subject(s) - linkage (software) , genetic linkage , simple (philosophy) , gene mapping , parametric statistics , computational biology , genetics , function (biology) , biology , gene , computer science , statistics , mathematics , chromosome , philosophy , epistemology
Linkage groups and orders are established through two‐point analysis; gene order is verified through simple three‐point analysis; linkage maps are obtained through weighted least squares, fitting observed θ values to those predicted by a parametric mapping function.
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