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Genetic analysis workshop III: Multilocus linkage analysis using PAP
Author(s) -
Bishop D. T.,
Can L. A.,
Hasstedt S. J.,
Skolnick M. H.
Publication year - 1985
Publication title -
genetic epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.301
H-Index - 98
eISSN - 1098-2272
pISSN - 0741-0395
DOI - 10.1002/gepi.1370020214
Subject(s) - linkage (software) , genetic linkage , genetics , locus (genetics) , biology , pairwise comparison , genetic analysis , statistics , gene , mathematics
Two linkage groups were identified through pairwise linkage analysis using PAP. Three‐locus analysis confirmed the suggested order of the loci within the linkage groups and was used to assess the strength of the conclusions. Strategies for improving the efficiency of linkage analysis are discussed.