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Genetic analysis workshop III: Multipoint linkage analysis
Author(s) -
Aston C. E.,
Wilson S. R.
Publication year - 1985
Publication title -
genetic epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.301
H-Index - 98
eISSN - 1098-2272
pISSN - 0741-0395
DOI - 10.1002/gepi.1370020212
Subject(s) - linkage (software) , pairwise comparison , genetic analysis , genetic linkage , genetics , recombination , biology , lod score , complete linkage , evolutionary biology , statistics , gene mapping , mathematics , gene , genotype , chromosome , single nucleotide polymorphism
It is possible to obtain an invalid set of estimates for the pairwise recombination values from using two‐point linkage analysis. Development of a multipoint linkage analysis which estimates the joint recombination events in a multilocus system is outlined.