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Genetics of the Lp lipoprotein in Japanese‐Americans
Author(s) -
Morton Newton E.,
Berg Kåre,
Dahlen Gösta,
Ferrell Robert E.,
Rhoads George G.,
Rao D. C.
Publication year - 1985
Publication title -
genetic epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.301
H-Index - 98
eISSN - 1098-2272
pISSN - 0741-0395
DOI - 10.1002/gepi.1370020202
Subject(s) - genetics , allele , biology , linkage (software) , gene , major gene , lipoprotein(a) , genetic linkage , lipoprotein , cholesterol , endocrinology
Segregation analysis of four Lp assays on 557 children in 227 families reveals a dominant major gene and a residual heritable component that may reflect one or more alleles of weaker effect. Close or moderate linkage to esterase‐D (ESD) is excluded.