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Skeletal myogenesis in the mouse esophagus does not occur through transdifferentiation
Author(s) -
Rishniw Mark,
Xin HongBo,
Deng KeYu,
Kotlikoff Michael I.
Publication year - 2003
Publication title -
genesis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.093
H-Index - 110
eISSN - 1526-968X
pISSN - 1526-954X
DOI - 10.1002/gene.10198
Subject(s) - transdifferentiation , myogenesis , skeletal muscle , biology , esophagus , microbiology and biotechnology , lineage (genetic) , mesoderm , embryonic stem cell , myocyte , anatomy , stem cell , genetics , gene
Summary: To determine the developmental history of murine esophageal skeletal muscle, smooth muscle cells were fate mapped by lineage‐specific recombination and phenotypically marked by eGFP. Examination of embryonic and postnatal tissues revealed that esophageal skeletal muscle does not arise from transdifferentiation of committed smooth muscle cells. genesis 36:81–82, 2003. © 2003 Wiley‐Liss, Inc.