Open AccessA Robust, Safe, and Scalable Magnetic Nanoparticle Workflow for RNA Extraction of Pathogens from Clinical and Wastewater Samples (Global Challenges 4/2021)
Author(s) -
RamosMandujano Gerardo,
Salunke Rahul,
Mfarrej Sara,
Rachmadi Andri Taruna,
Hala Sharif,
Xu Jinna,
Alofi Fadwa S.,
Khogeer Asim,
Hashem Anwar M.,
Almontashiri Naif A. M.,
Alsomali Afrah,
Shinde Digambar B.,
Hamdan Samir,
Hong PeiYing,
Pain Arnab,
Li Mo
Publication year - 2021
Publication title -
global challenges
Language(s) - English
Resource type - Journals
ISSN - 2056-6646
DOI - 10.1002/gch2.202170041
Subject(s) - bottleneck , workflow , isolation (microbiology) , scalability , rna extraction , economic shortage , wastewater , magnetic nanoparticles , pandemic , covid-19 , rna , virology , computer science , nanotechnology , engineering , waste management , nanoparticle , medicine , biology , microbiology and biotechnology , materials science , embedded system , operating system , pathology , biochemistry , disease , gene , philosophy , database , government (linguistics) , linguistics , infectious disease (medical specialty)
A critical bottleneck in COVID‐19 diagnosis and surveillance is the shortage of kits for RNA extraction. In article number 2000068, Mo Li and co‐workers develop a DIY, open‐source, safe, and fast method for magnetic‐nanoparticle‐aided viral RNA isolation from contagious samples (MAVRICS). MAVRICS rivals commercial kits in performance and could become an enabling technology for community testing and wastewater monitoring in the current and future pandemics.