Open AccessDisposable Microfluidic Sensor Based on Nanocellulose for Glucose Detection
Author(s) -
Uddin Khan Mohammad Ahsan,
Jokinen Ville,
Jahangiri Farzin,
Franssila Sami,
Rojas Orlando J.,
Tuukkanen Sampo
Publication year - 2019
Publication title -
global challenges
Language(s) - English
Resource type - Journals
ISSN - 2056-6646
DOI - 10.1002/gch2.201800079
Subject(s) - nanocellulose , microfluidics , software portability , nanotechnology , fluidics , glucose oxidase , biosensor , materials science , computer science , chemistry , cellulose , engineering , biochemistry , aerospace engineering , programming language
Point‐of‐care devices that are inexpensive, disposable, and environmentally friendly are becoming increasingly predominant in the field of biosensing and biodiagnostics. Here, microfluidics is a suitable option to endow portability and minimal reagent and material consumption. Nanocellulose is introduced to manufacture microfluidic channels and as a storage and immobilization compartment of glucose oxidase. Improved enzymatic activity retention is demonstrated in a simple and disposable point‐of‐care diagnostic unit that is able to detect glucose from fluid matrices at 0.1 × 10 −3 m concentration and in less than 10 min. It is concluded that the patterning and fluidic technologies that are possible with nanocellulose enable easily scalable multianalyte designs.