Analysis of the wilms tumor suppressor gene  WT1  in endometrial carcinoma | Zendy

Rackley Raymond | Zendy; Casey Graham | Zendy; Zhao XiaoIan | Zendy; Miller David W. | Zendy; Williams Bryan R. G. | Zendy; Coppes Max J. | Zendy

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Analysis of the wilms tumor suppressor gene WT1 in endometrial carcinoma

Author(s) -

Rackley Raymond,

Casey Graham,

Zhao XiaoIan,

Miller David W.,

Williams Bryan R. G.,

Coppes Max J.

Publication year - 1995

Publication title -

genes, chromosomes and cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.754

H-Index - 119

eISSN - 1098-2264

pISSN - 1045-2257

DOI - 10.1002/gcc.2870140411

Subject(s) - wilms' tumor , tumor suppressor gene , suppressor , cancer research , malignancy , carcinoma , gene , endometrial cancer , biology , oncology , medicine , cancer , carcinogenesis , genetics

This study reports on the evaluation of the Wilms tumor suppressor gene WT1 in 14 endometrial carcinomas. Despite the fact that several endometrial carcinomas were shown to express WT1 , we were unable to demonstrate mutations in the MT1 zinc finger region, suggesting that WT1 does not play a prominent role in the etiology of this malignancy.

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