A second case of trisomy 8 in philadelphia chromosome (Ph)‐negative cells during the course of Ph‐positive chronic myelocytic leukemia | Zendy

BilhouNabera C. | Zendy; Marit G. | Zendy; Devianne I. | Zendy; Viard F. | Zendy; Salzes S. | Zendy; Montastruc M. | Zendy; Renoux M. | Zendy; Broustet A. | Zendy; Reiffers J. | Zendy; Bernard Ph. | Zendy

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A second case of trisomy 8 in philadelphia chromosome (Ph)‐negative cells during the course of Ph‐positive chronic myelocytic leukemia

Author(s) -

BilhouNabera C.,

Marit G.,

Devianne I.,

Viard F.,

Salzes S.,

Montastruc M.,

Renoux M.,

Broustet A.,

Reiffers J.,

Bernard Ph.

Publication year - 1993

Publication title -

genes, chromosomes and cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.754

H-Index - 119

eISSN - 1098-2264

pISSN - 1045-2257

DOI - 10.1002/gcc.2870060414

Subject(s) - clone (java method) , trisomy , myelocytic leukemia , philadelphia chromosome , trisomy 8 , peripheral blood , medicine , leukemia , chromosome , microbiology and biotechnology , immunology , chemistry , biology , karyotype , genetics , chromosomal translocation , dna , gene

A Ph‐positive CML patient who had received a peripheral blood stem cell autograft in chronic phase demonstrated a transient regression of the Ph‐positive clone with the concurrent appearance of another clone with trisomy 8. This latter clone disappeared when the patient received α‐interferon. © 1993 Wiley‐Liss, Inc.

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