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Rearrangement of band q13 on both chromosomes 12 in a periosteal chondroma
Author(s) -
Mandahl Nils,
Willén Helena,
Rydholm Anders,
Heim Sverre,
Mitelman Felix
Publication year - 1993
Publication title -
genes, chromosomes and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.754
H-Index - 119
eISSN - 1098-2264
pISSN - 1045-2257
DOI - 10.1002/gcc.2870060210
Subject(s) - dicentric chromosome , chromosomal translocation , chondroma , chromosome , chromosomal rearrangement , karyotype , ring chromosome , biology , chromosome 12 , genetics , anatomy , gene
Cytogenetic analysis of a recurrent periosteal chondroma revealed nonreciprocal translocations of both chromosomal segments 12q13→qter, from one chromosome 12 to 7q32 and from the homologous chromosome 12 to 16q22. The remaining parts of the two chromosomes 12 formed a dicentric chromosome. This is the second reported chondroma with a 12q13‐15 rearrangement, and changes of this chromosome region consequently seem to be nonrandom occurrences in chondromas. © 1993 Wiley‐Liss, Inc.

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