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Variant translocations in two Burkitt's lymphoma cell lines are located in the MLV14 locus
Author(s) -
Galiego Marta I.,
Lazo Pedro A.
Publication year - 1992
Publication title -
genes, chromosomes and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.754
H-Index - 119
eISSN - 1098-2264
pISSN - 1045-2257
DOI - 10.1002/gcc.2870050317
Subject(s) - locus (genetics) , chromosomal translocation , burkitt's lymphoma , lymphoma , biology , cell culture , cancer research , microbiology and biotechnology , genetics , gene , immunology
The human MLV14 locus, located 20 kilobases 3′ of MYC , is rearranged in two Burkitt's lymphoma cell lines with either a t(2;8)(p 12;q24) or t(8;22)(q24;q 11). Alterations of MLV14 may have prognostic significance in some types of B‐cell malignancies.