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Cytogenetic analysis of renal angiomyolipoma
Author(s) -
DebiecRychter Maria,
SaryuszWolska Hanna,
Salagierski Marek
Publication year - 1992
Publication title -
genes, chromosomes and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.754
H-Index - 119
eISSN - 1098-2264
pISSN - 1045-2257
DOI - 10.1002/gcc.2870040118
Subject(s) - angiomyolipoma , medicine , kidney
Chromosome analysis of a benign, unilateral, renal angiomyolipoma revealed the karyotype 44,XX, –8, –12, –14, –21, + der (8q14q), + der(12)(12pter → 12q14‐15:: 12q24 → 12q14–15::21q21 → 21 qter). This indicates that structural changes of 12q13‐15, which are so frequently observed in the common malignant and benign lipogenic tumors, may also occur in the rarer variants of these neoplasms.

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