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Chromosome abnormalities in multiple meningiomas of a child
Author(s) -
Wullich Bernd,
Mayfrank Lothar,
Schwechheimer Karl,
Finke Jürgen,
Schempp Werner
Publication year - 1990
Publication title -
genes, chromosomes and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.754
H-Index - 119
eISSN - 1098-2264
pISSN - 1045-2257
DOI - 10.1002/gcc.2870020214
Subject(s) - monosomy , meningioma , chromosome , karyotype , genetics , medicine , biology , pathology , gene
We report the cytogenetic findings in two meningiomas from a child presenting with multiple meningiomas. In contrast to the chromosomal profile of adult meningiomas, both tumors studied revealed excess of chromosomes in addition to monosomy 22. This difference is remarkable considering several reports indicating that childhood meningiomas behave differently and have a worse prognosis than those in adults.