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Proposals for standardized protocols for cytogenetic analyses of acute leukemias, chronic lymphocytic leukemia, chronic myeloid leukemia, chronic myeloproliferative disorders, and myelodysplastic syndromes
Author(s) -
Haferlach Claudia,
Rieder Harald,
Lillington Debra M.,
Dastugue Nicole,
Hagemeijer Anne,
Harbott Jochen,
Stilgenbauer Stephan,
Knuutila Sakari,
Johansson Bertil,
Fonatsch Christa
Publication year - 2007
Publication title -
genes, chromosomes and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.754
H-Index - 119
eISSN - 1098-2264
pISSN - 1045-2257
DOI - 10.1002/gcc.20433
Subject(s) - medicine , myelodysplastic syndromes , myeloid leukemia , chronic lymphocytic leukemia , fluorescence in situ hybridization , myeloproliferative disorders , philadelphia chromosome , cytogenetics , leukemia , oncology , chromosome , bone marrow , biology , gene , chromosomal translocation , biochemistry
The impact of cytogenetic characterization based on chromosome banding analyses and fluorescence in situ hybridization on clinical decision making has increased dramatically during recent years. Therefore, laboratory techniques have to be optimized to provide reliable results for optimal patient care. In addition, quick and correct results save time and money by preventing unnecessary additional diagnostics and suboptimal treatment approaches. It was our aim to present proposals for standardized protocols to improve the diagnosis, and hence the treatment outcome, of hematologic malignancies. © 2007 Wiley‐Liss, Inc.