A Computational Framework for Patient‐Specific Analysis of Articular Cartilage Incorporating Structural Information from DT‐MRI | Zendy

Pierce David M. | Zendy; Trobin Werner | Zendy; Holzapfel Gerhard A. | Zendy

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A Computational Framework for Patient‐Specific Analysis of Articular Cartilage Incorporating Structural Information from DT‐MRI

Author(s) -

Pierce David M.,

Trobin Werner,

Holzapfel Gerhard A.

Publication year - 2009

Publication title -

gamm‐mitteilungen

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.239

H-Index - 18

eISSN - 1522-2608

pISSN - 0936-7195

DOI - 10.1002/gamm.200910014

Subject(s) - articular cartilage , magnetic resonance imaging , indentation , diffusion mri , computer science , deformation (meteorology) , cartilage , biomedical engineering , materials science , artificial intelligence , engineering , osteoarthritis , medicine , anatomy , pathology , radiology , composite material , alternative medicine

Accurate techniques for simulating sof t biological tissue deformation are an increasingly valuable tool in many areas of biomechanical analysis and medical image computing. To model the morphology and the material response of human articular cartilage a phenomenological and patient‐specific simulation approach incorporating the collagen fibre fabric is proposed. We then demonstrate a unique combination of ultra‐high field Diffusion Tensor Magnetic Resonance Imaging (17.6T DT‐MRI) and a novel numerical approach incorporating the empirical data to predict the collagen fibre fabric deformation for an indentation experiment (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)

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