Open AccessResveratrol: A miraculous natural compound for diseases treatment
Author(s) -
Koushki Mehdi,
AmiriDashatan Nasrin,
Ahmadi Nayebali,
Abbaszadeh HojjatAllah,
RezaeiTavirani Mostafa
Publication year - 2018
Publication title -
food science and nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.614
H-Index - 27
ISSN - 2048-7177
DOI - 10.1002/fsn3.855
Subject(s) - resveratrol , phytoalexin , disease , polyphenol , diabetes mellitus , antioxidant , medicine , pharmacology , natural compound , traditional medicine , biology , biochemistry , endocrinology , biochemical engineering , engineering
Resveratrol (3, 5, 4′‐trihydroxystilbene) is a nonflavonoid polyphenol that naturally occurs as phytoalexin. It is produced by plant sources such as grapes, apples, blueberries, plums, and peanut. This compound has critical roles in human health and is well known for its diverse biological activities such as antioxidant and anti‐inflammatory properties. Nowadays, due to rising incidence of different diseases such as cancer and diabetes, efforts to find novel and effective disease‐protective agents have led to the identification of plant‐derived compounds such as resveratrol. Furthermore, several in vitro and in vivo studies have revealed the effectiveness of resveratrol in various diseases such as diabetes mellitus, cardiovascular disease, metabolic syndrome, obesity, inflammatory, neurodegenerative, and age‐related diseases. This review presents an overview of currently available studies on preventive properties and essential molecular mechanisms involved in various diseases.