Open AccessMechanistic role of astaxanthin derived from shrimp against certain metabolic disorders
Author(s) -
Yaqoob Zubda,
Arshad Muhammad Sajid,
Imran Muhammad,
Munir Haroon,
Qaisrani Tahira Batool,
Khalid Waseem,
Asghar Zubia,
Suleria Hafiz Ansar Rasul
Publication year - 2022
Publication title -
food science and nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.614
H-Index - 27
ISSN - 2048-7177
DOI - 10.1002/fsn3.2623
Subject(s) - astaxanthin , antioxidant , oxidative stress , polyunsaturated fatty acid , carotenoid , disease , shrimp , biochemistry , chemistry , biology , medicine , pharmacology , fishery , fatty acid
Abstract Oxidative stress caused by the imbalance between production of oxidants and antioxidants in the body leads to the development of different ailments. The bioactive compounds derived from marine sources are considered to be safe and appropriate to use. Astaxanthin possesses antioxidant activity about 100–500 times higher than other antioxidants such as α‐tocopherol and β‐carotene. It has numerous health benefits and vital pharmacological properties for the treatment of diseases like diabetes, hypertension, cancer, heart disease, ischemia, neurological disorders, and potential role in liver enzyme gamma‐glutamyl transpeptidase which has significance in medicine as a diagnostic marker. The primary source of astaxanthin among crustaceans is shrimps and the presence of astaxanthin protects shrimps from oxidation of polyunsaturated fatty acids and cholesterol. Conclusively, astaxanthin derived from shrimps is very effective against oxidative stress which can lead to certain ailments.