Open AccessCysteine and homocysteine as biomarker of various diseases
Author(s) -
Rehman Tahniat,
Shabbir Muhammad Asim,
InamUrRaheem Muhammad,
Manzoor Muhammad Faisal,
Ahmad Nazir,
Liu ZhiWei,
Ahmad Muhammad Haseeb,
Siddeeg Azhari,
Abid Muhammad,
Aadil Rana Muhammad
Publication year - 2020
Publication title -
food science and nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.614
H-Index - 27
ISSN - 2048-7177
DOI - 10.1002/fsn3.1818
Subject(s) - hyperhomocysteinemia , homocysteine , biomarker , cysteine , methionine , medicine , amino acid , biochemistry , chemistry , enzyme
Cysteine and homocysteine (Hcy), both sulfur‐containing amino acids (AAs), produced from methionine another sulfur‐containing amino acid, which is converted to Hcy and further converted to cysteine. This article aims to highlight the link between cysteine and Hcy, and their mechanisms, important functions, play in the body and their role as a biomarker for various types of diseases. So that using cysteine and Hcy as a biomarker, we can prevent and diagnose many diseases. This review concluded that hyperhomocysteinemia (elevated levels of homocysteine) is considered as toxic for cells and is associated with different health problems. Hyperhomocysteinemia and low levels of cysteine associated with various diseases like cardiovascular diseases (CVD), ischemic stroke, neurological disorders, diabetes, cancer like lung and colorectal cancer, renal dysfunction‐linked conditions, and vitiligo.