Open AccessTigecycline: a novel broad spectrum antibiotic
Author(s) -
Nathwani Dilip
Publication year - 2006
Publication title -
future prescriber
Language(s) - English
Resource type - Journals
eISSN - 1931-2261
pISSN - 1468-9871
DOI - 10.1002/fps.23
Subject(s) - tigecycline , medicine , antibiotics , incidence (geometry) , broad spectrum , antibiotic resistance , intensive care medicine , linezolid , hygiene , pediatrics , emergency medicine , microbiology and biotechnology , biology , staphylococcus aureus , bacteria , vancomycin , physics , optics , pathology , chemistry , genetics , combinatorial chemistry
Healthcare associated infections (HAIs) affect around 2 million people admitted to acute care hospitals in the USA. 1 Approximately 9 per cent of patients in UK hospitals suffer from an infection acquired during their hospital stay, 2 many of which are due to multi‐resistant, Gram‐positive and Gram‐negative patho‐gens. The incidence of colonisation and infection with these pathogens continues to rise due to failures in hospital hygiene, selective pressures created by overuse of antibiotics, and mobile elements that can enc‐ode bacterial resistance mechanisms. Copyright © 2006 John Wiley & Sons, Ltd.