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Auto‐regulation and blood flow in the cerebral circulation
Author(s) -
David Tim,
Brown Michael,
Ferrandez A.
Publication year - 2003
Publication title -
international journal for numerical methods in fluids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 112
eISSN - 1097-0363
pISSN - 0271-2091
DOI - 10.1002/fld.495
Subject(s) - computational fluid dynamics , circle of willis , computer science , flow (mathematics) , circulation (fluid dynamics) , mechanics , marine engineering , geology , engineering , physics , anatomy , medicine
The application of computational fluid dynamics (CFD) to model biological flows is quite a recent one. This study presents a CFD model of the Circle of Willis developed to simulate the human cerebrovascular tree. Specifically, we aim to show firstly how the auto‐regulation mechanism can be modelled and secondly how smaller arteries, often not visible by non‐intrusive MR studies, can be detected by making use of the results obtained from the computer simulation. Results show the time‐varying mass flow in each of the efferent vessels and how collateral vessels are even used in naturally ‘balanced’ configurations. Copyright © 2003 John Wiley & Sons, Ltd.