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Numerical studies of blood flow in healthy, stenosed, and stented carotid arteries
Author(s) -
Gay Mickaël,
Zhang Lucy T.
Publication year - 2008
Publication title -
international journal for numerical methods in fluids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.938
H-Index - 112
eISSN - 1097-0363
pISSN - 0271-2091
DOI - 10.1002/fld.1966
Subject(s) - pulsatile flow , restenosis , shear stress , hemodynamics , cardiology , blood flow , medicine , carotid arteries , artery , biomedical engineering , stent , materials science , composite material
Numerical analysis of pulsatile blood flow in healthy, stenosed, and stented carotid arteries is performed with the aim of identifying hemodynamic factors in the initiation, growth, and the potential of leading to severe occlusions of a diseased artery. The Immersed Finite Element Method is adopted for this study to conveniently incorporate various geometrical shapes of arteries without remeshing. Our computational results provide detailed quantitative analysis on the blood flow pattern, wall shear stress, particle residence time, and oscillatory shear index. The analysis of these parameters leads to a better understanding of blood clot formation and its localization in a stenosed and a stented carotid artery. A healthy artery is also studied to establish a baseline comparison. This analysis will assist in developing treatments for diseased arteries and novel stent designs to reduce restenosis. Copyright © 2008 John Wiley & Sons, Ltd.