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Synthesis of thiophene derivatives with long‐lasting citrusy type odour
Author(s) -
Kost Bartłomiej,
Matysiak Sylwia,
Kula Józef,
Bonikowski Radosław
Publication year - 2018
Publication title -
flavour and fragrance journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.393
H-Index - 70
eISSN - 1099-1026
pISSN - 0882-5734
DOI - 10.1002/ffj.3442
Subject(s) - chemistry , thiophene , enantiomer , organic chemistry
Starting from 3‐methylthiophene, 11 new sensory‐active thiophene derivatives were synthesized. Among them, 3‐(5‐butyl‐3‐methylthiophen‐2‐yl)‐1‐methylpropyl acetate ( 3 ), 2,5‐dibutyl‐3‐methylthiophene, and 1‐methyl‐3‐(3‐methylthiophen‐2‐yl)propyl acetate ( 12 ) were characterized by long‐lasting citrus scents. The individual enantiomers of esters 3 and 12 , which have been characterized in terms of fragrance, were also obtained.