Premium
Evolutionary trace of human odorant receptors of chromosome 17
Author(s) -
Knape Kirsten,
Beyer Anton,
Stary Anna,
Buchbauer Gerhard,
Wolschann Peter
Publication year - 2009
Publication title -
flavour and fragrance journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.393
H-Index - 70
eISSN - 1099-1026
pISSN - 0882-5734
DOI - 10.1002/ffj.1933
Subject(s) - pseudogene , gene , genome , human genome , chromosome , gene duplication , gene cluster , function (biology) , receptor , genetics , biology , computational biology , evolutionary biology
Studies on the odorant receptor cluster located on human chromosome 17, which contains 18 odorant receptor genes, are presented. After an extended search for orthologues of those odorant receptor genes in chimpanzee, rat and mouse genomes, comparisons subject to genomic location, similarities and function were made. Different ways of evolutionary propagation can be observed. This leads to conversion into pseudogenes, but also duplication of some genes occurs. Copyright © 2009 John Wiley & Sons, Ltd.