Composition and antituberculosis activity of the volatile oil of  Heliotropium indicum  Linn. growing in Phitsanulok, Thailand | Zendy

Machan Theeraphan | Zendy; Korth John | Zendy; Liawruangrath Boonsom | Zendy; Liawruangrath Saisunee | Zendy; Pyne Stephen G. | Zendy

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Composition and antituberculosis activity of the volatile oil of Heliotropium indicum Linn. growing in Phitsanulok, Thailand

Author(s) -

Machan Theeraphan,

Korth John,

Liawruangrath Boonsom,

Liawruangrath Saisunee,

Pyne Stephen G.

Publication year - 2006

Publication title -

flavour and fragrance journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.393

H-Index - 70

eISSN - 1099-1026

pISSN - 0882-5734

DOI - 10.1002/ffj.1577

Subject(s) - chemistry , essential oil , chromatography , linalool , gas chromatography , steam distillation , gas chromatography–mass spectrometry , monoterpene , mass spectrometry , traditional medicine , organic chemistry , medicine

The volatile oil from the aerial parts of H. indicum was isolated by hydrodistillation and analysed by a combination of gas chromatography (GC–FID) and gas chromatography–mass spectrometry (GC–MS). The essential oil was obtained in 0.004% yield as a light brown liquid. The major constituents of the volatile oil of H. indicum were phytol (49.1%), 1‐dodecanol (6.4%) and β ‐linalool (3.0%). In addition, the volatile oil showed significant antituberculosis activity against Mycobacterium tuberculosis H37Ra in the Alamar blue assay system with an MIC of 20.8 µg/ml. Copyright © 2005 John Wiley & Sons, Ltd.

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