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Antifungal efficacy of Taxodium and Mentha oils against some human pathogenic fungi
Author(s) -
Pandey K. P.,
Shahi S. K.,
Singh R.,
Dutta S.,
Dikshit A.
Publication year - 2002
Publication title -
flavour and fragrance journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.393
H-Index - 70
eISSN - 1099-1026
pISSN - 0882-5734
DOI - 10.1002/ffj.1125
Subject(s) - microsporum gypseum , epidermophyton floccosum , chemistry , mycelium , minimum inhibitory concentration , potency , antifungal , microbiology and biotechnology , botany , biology , traditional medicine , trichophyton , antimicrobial , in vitro , biochemistry , medicine
During antifungal screening of essential oils of some higher plants against human pathogenic fungi, oils of Mentha spicata (L.) and Taxodium distichum (L.) Rich. exhibited significant activity against the test pathogens Epidermophyton floccosum (Harz) Langeron and Milochevitch, Microsporum gypseum (Bodin.) Guiart and Gregoraki and Microsporum nanum Fuentes. The minimum inhibitory concentrations (MICs) of the oil of M. spicata were found to be 1.8µl/ml for E. floccosum, M. gypseum and M . nanum . In the case of T. distichum the minimum inhibitory concentrations (MICs) were found to be 2.0µl/ml for M. gypseum and 2.5 µl/ml for E. floccosum and M. nanum . The oils also exhibited potency against heavy doses of inoculum (30 mycelial discs, each 5 mm in diameter) at these MICs concentrations. On comparison with the synthetic antifungal drugs myconazole and ketaconazole, these oils were found to be more effective. Copyright © 2002 John Wiley & Sons, Ltd.