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A micelle inhibition model for the bioavailability of polycyclic aromatic hydrocarbons in aquatic systems
Author(s) -
Park Seok S.,
Park JaeWoo,
Uchrin Christopher,
Cheney Marcos A.
Publication year - 2002
Publication title -
environmental toxicology and chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.1
H-Index - 171
eISSN - 1552-8618
pISSN - 0730-7268
DOI - 10.1002/etc.5620211230
Subject(s) - bioconcentration , micelle , bioavailability , pulmonary surfactant , chemistry , partition coefficient , environmental chemistry , bioaccumulation , critical micelle concentration , fluoranthene , chrysene , phenanthrene , anthracene , aquatic ecosystem , chromatography , organic chemistry , aqueous solution , biology , biochemistry , bioinformatics
A mathematical model was developed to quantify micelle suppression on the bioavailability of hydrophobic organic compounds in aquatic systems. The model was based on a three‐compartment dynamic system in which the hydrophobic compounds are taken up and eliminated by organisms with an equilibrium partitioning between water and micelle. The model was validated against data obtained from in vitro studies of the bioaccumulation of naphthalene, anthracene, and chrysene into the gills of the freshwater mussel ( Ellipto complanata ) in the presence of a surfactant (Tween 80). The model predictions agreed well with the experimental results for all three chemicals. Sensitivity analyses were performed to examine model responses to the surfactant parameters. From the model, we derive an equation for a bioconcentration factor in aquatic surfactant systems to predict the maximum concentration of polycyclic aromatic hydrocarbons (PAHs) in aquatic organisms. From these results, we also propose a micelle inhibition factor for bioconcentration that is a function of the surfactant concentration, critical micelle concentration, and partition coefficient of hydrophobic compounds between water and micelle. Knowledge of these parameters may improve understanding of the partitioning of PAHs into organisms in the presence of surfactants.