Estimating and testing bioconcentration factors | Zendy

Bailer A. John | Zendy; Walker Sean E. | Zendy; Venis Kyle J. | Zendy

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Estimating and testing bioconcentration factors

Author(s) -

Bailer A. John,

Walker Sean E.,

Venis Kyle J.

Publication year - 2000

Publication title -

environmental toxicology and chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.1

H-Index - 171

eISSN - 1552-8618

pISSN - 0730-7268

DOI - 10.1002/etc.5620190925

Subject(s) - bioconcentration , hyalella azteca , confidence interval , environmental chemistry , organism , environmental science , chemistry , toxicology , statistics , bioaccumulation , ecology , biology , mathematics , amphipoda , paleontology , crustacean

Bioconcentration factors (BCFs) are commonly calculated to represent the equilibrium concentration of a substance in an organism relative to environmental concentrations of the same substance. The BCF is derived from parameters estimated in uptake and elimination experiments and is presented as a single value without error estimates or confidence intervals. However, it is desirable to know the variability/precision of the BCF estimate and to statistically compare BCFs among experimental conditions. In this study, the calculation of standard errors and confidence intervals for BCFs is presented. In addition, a statistical method for formally comparing the BCFs derived under two or more experimental conditions is discussed. These methods are illustrated using data from a study of DDT‐exposed Hyalella azteca and Diporeia spp.

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