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Effects of physical (hypoxia, hyperoxia) and chemical (potassium dichromate, fenitrothion) stress on antioxidant enzyme activities in Chironomus riparius mg. (diptera, chironomidae) larvae: Potential biomarkers
Author(s) -
Choi Jinhee,
Roche Hélène,
Caquet Thierry
Publication year - 2000
Publication title -
environmental toxicology and chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.1
H-Index - 171
eISSN - 1552-8618
pISSN - 0730-7268
DOI - 10.1002/etc.5620190231
Subject(s) - potassium dichromate , catalase , chemistry , antioxidant , glutathione peroxidase , superoxide dismutase , fenitrothion , glutathione reductase , glutathione , hyperoxia , biochemistry , chironomus riparius , hemolymph , enzyme , botany , biology , chironomidae , larva , pesticide , ecology , oxygen , inorganic chemistry , organic chemistry
Effects of physical (hypoxia, hyperoxia) and chemical (potassium dichromate, fenitrothion) stress on antioxidant enzyme activities and hemoglobin content in Chironomus riparius Mg. (Diptera, Chironomidae) larvae were evaluated under laboratory conditions in order to identify pertinent biomarkers of stress. Hypoxia and hyperoxia caused an increase in Cu,Zn‐superoxide dismutase (SOD) and Mn‐SOD activities and a simultaneous decrease in total peroxidase (Px) and glutathione peroxidase (GSH‐Px) activities. A parallel increase in hemoglobin concentration in the hemolymph was observed. The exposure to sublethal concentrations of both potassium dichromate and fenitrothion led to an increase in Cu,Zn‐SOD and Mn‐SOD activities and to a decrease in GSH‐Px activity. Activation of catalase (CAT) was observed in the larvae exposed to high fenitrothion concentration (20μg/L). The response of SODs was rapid and sensitive to low chemical concentrations, but changes in CAT, Px, and GSH‐Px were more specific and less sensitive.