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Sex—specific vitellogenin production in immature rainbow trout
Author(s) -
Carlson David B.,
Williams David E.
Publication year - 1999
Publication title -
environmental toxicology and chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.1
H-Index - 171
eISSN - 1552-8618
pISSN - 0730-7268
DOI - 10.1002/etc.5620181033
Subject(s) - rainbow trout , vitellogenin , xenoestrogen , juvenile , biology , trout , fish <actinopterygii> , medicine , endocrinology , salmonidae , zoology , fishery , ecology , genetics , cancer , estrogen receptor , breast cancer
Vitellogenin (Vg) was measured in sexually immature rainbow trout ( Oncorhynchus mykiss ) exposed to 17β‐estradiol (E 2 ) in the diet. Mixed—sex populations of trout aged 3, 6, 12, or 18 months were maintained separately and fed E 2 at 0.05 or 2.5 mg/kg for 7 d. Females fed E 2 at 0.05 mg/kg consistently produced three‐ to fourfold greater amounts of Vg than similarly aged males. Age‐ and sex—matched fish fed E 2 at 2.5 mg/kg produced equivalent amounts of Vg. Sex differences in Vg production were apparent only at a dose of E 2 (0.05 mg/kg) that results in submaximal Vg induction. Our results document the importance of considering the sex of juvenile fish when using Vg production as a marker of xenoestrogen exposure.