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Biodehalogenation, reductive dehalogenation by Methanobacterium Thermoautotrophicum . Comparison with nickel(I)octaethylisobacteriochlorin anion. An F‐430 model
Author(s) -
Castro C.E.,
Helvenston M.C.,
Belser N.O.
Publication year - 1994
Publication title -
environmental toxicology and chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.1
H-Index - 171
eISSN - 1552-8618
pISSN - 0730-7268
DOI - 10.1002/etc.5620130310
Subject(s) - halogenation , chloroform , chemistry , nickel , tetrachloroethylene , chloride , reductive dechlorination , medicinal chemistry , chloroacetic acid , ethylene , cyclohexane , carbon tetrachloride , nuclear chemistry , inorganic chemistry , organic chemistry , trichloroethylene , catalysis , biodegradation
The reductive dehalogenation of 1,1,2‐tnchloroethane, chloroform, fluorotrichloromethane, carbon tetrachloride, 1,1,1‐tnchloroethane, and ethylene dichlonde by Methanobactenum thermoautotrophicum occurs slowly at 60°C in the listed order. Vinyl chloride and chloroacetic acid are inert. The average t 1/2 for nearly all substrates is approximately 100 h and varies by a factor of approximately two. In contrast, an active site model for factor F‐430, Ni 1 octaethyhsobactenochlorin, brings about the same transformations with astonishing speed and vast differences in specific rates It is suggested that despite the enormous reducing capacity of this anaerobe, the overall reduction process is limited by permeation factors.