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Cadmium turnover in minnows ( phoxinus phoxinus ) preexposed to waterborne cadmium
Author(s) -
Glynn Anders Wicklund,
Olsson PerErik
Publication year - 1991
Publication title -
environmental toxicology and chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.1
H-Index - 171
eISSN - 1552-8618
pISSN - 0730-7268
DOI - 10.1002/etc.5620100311
Subject(s) - metallothionein , gill , cadmium , phoxinus , cytosol , chemistry , kidney , environmental chemistry , fish <actinopterygii> , biology , biochemistry , endocrinology , cyprinidae , fishery , organic chemistry , enzyme
The radioactive isotope 109 Cd was used to study the turnover of Cd in minnows ( Phoxinus phoxinus ) preexposed to waterborne Cd. Three groups of fish were preexposed to 3 nM Cd for 0, 30 and 91 d before a 24‐h 109 Cd exposure (3 nM Cd). The effect of preexposure on the turnover of 109 Cd in the fish was studied during a 64‐d post‐tracer exposure period at 3 nM Cd. The major effect of Cd preexposure on the 109 Cd turnover was a decreased uptake of 109 Cd into the gills. In the gill tissue, the 109 Cd was retained by Cd binding ligands mainly in the cytosolic fraction. Preexposure decreased the percentage of 109 Cd retained in a cytosolic high‐molecular‐weight fraction at the end of the tracer exposure. At the same time, an increased percentage of tracer was retained in a low‐molecular‐weight cytosolic fraction with high 109 Cd content (Cd‐BP), probably metallothionein (MT). This effect was not caused by an increased MT content in the preexposed fish. The liver, kidney, muscle and bone accumulated 109 Cd, while the gills, head and skin eliminated tracer during the 64‐d post‐tracer exposure period. The 109 Cd elimination and accumulation were not altered by the Cd preexposure. A large part of the tracer accumulated in the liver and kidney was detected in the Cd‐BP fraction, and the MT content in the organs was not altered by the preexposure.