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Perfluoroalkyl Substances Increase Susceptibility of Northern Leopard Frog Tadpoles to Trematode Infection
Author(s) -
Brown Sophia R.,
Flynn R. Wesley,
Hoverman Jason T.
Publication year - 2021
Publication title -
environmental toxicology and chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.1
H-Index - 171
eISSN - 1552-8618
pISSN - 0730-7268
DOI - 10.1002/etc.4678
Subject(s) - leopard frog , lithobates , biology , larva , leopard , zoology , amphibian , ecology
Per/polyfluoroalkyl substances (PFAS) are contaminants of emerging concern that can impair immune function, yet few studies have tested whether exposure increases infection risk. Using laboratory experiments, we found that exposure to 10 ppb of perfluorohexanesulfonic acid increased trematode ( Echinoparyphium lineage 3) infections in larval northern leopard frogs ( Lithobates pipiens ). However, there was no effect of perfluorooctanesulfonic acid. Our results demonstrate that PFAS can potentially enhance infection risk in natural systems. Environ Toxicol Chem 2021;40:689–694. © 2020 SETAC