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Comparison of the General Threshold Model of Survival and Dose–Response Models in Simulating the Acute Toxicity of Metals to Danio rerio
Author(s) -
He An,
Liu Xinyong,
Qu Liang,
Gao Yongfei,
Feng Jianfeng,
Zhu Lin
Publication year - 2019
Publication title -
environmental toxicology and chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.1
H-Index - 171
eISSN - 1552-8618
pISSN - 0730-7268
DOI - 10.1002/etc.4534
Subject(s) - danio , zebrafish , acute toxicity , toxicity , cadmium , toxicology , chemistry , environmental chemistry , biology , biochemistry , organic chemistry , gene
We exposed zebrafish ( Danio rerio ) to different concentrations of lead and cadmium, and monitored them for survival at 24, 48, 72, and 96 h. Metal toxicity was predicted and compared using the dose–response and general threshold survival models in terms of required data sets, fit performance, and applicability. Environ Toxicol Chem 2019;38:2169–2177. © 2019 SETAC.