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Review of recent proteomic applications in aquatic toxicology
Author(s) -
Sanchez Brian C.,
RalstonHooper Kimberly,
Sepúlveda María S.
Publication year - 2011
Publication title -
environmental toxicology and chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.1
H-Index - 171
eISSN - 1552-8618
pISSN - 0730-7268
DOI - 10.1002/etc.402
Subject(s) - proteomics , aquatic toxicology , fish <actinopterygii> , biology , computational biology , data science , computer science , chemistry , fishery , toxicity , biochemistry , organic chemistry , gene
Over the last decade, the environmental sciences have witnessed an incredible movement towards the utilization of high‐throughput molecular tools that are capable of detecting simultaneous changes of hundreds, and even thousands, of molecules and molecular components after exposure of organisms to different environmental stressors. These techniques have received a great deal of attention because they not only offer the potential to unravel novel mechanisms of physiological and toxic action but are also amenable to the discovery of biomarkers of exposure and effects. In this article, we review the state of knowledge of one of these tools in ecotoxicological research: proteomics. We summarize the state of proteomics research in fish, and follow with studies conducted with aquatic invertebrates. A brief discussion on proteomic methods is also presented. We conclude with some ideas for future proteomic studies with fish and aquatic invertebrates. Environ. Toxicol. Chem. 2011;30:274–282. © 2010 SETAC