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Occurrence and human dietary assessment of fluoroquinolones antibiotics in cultured fish around Tai Lake, China
Author(s) -
Song Chao,
Zhang Cong,
Kamira Barry,
Qiu Liping,
Fan Limin,
Wu Wei,
Meng Shunlong,
Hu Gengdong,
Chen Jiazhang
Publication year - 2017
Publication title -
environmental toxicology and chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.1
H-Index - 171
eISSN - 1552-8618
pISSN - 0730-7268
DOI - 10.1002/etc.3876
Subject(s) - enrofloxacin , aquaculture , shrimp , perch , fishery , biology , antibiotics , zoology , tolerable daily intake , veterinary medicine , toxicology , fish <actinopterygii> , medicine , body weight , ciprofloxacin , microbiology and biotechnology , endocrinology
Fluoroquinolone antibiotics are widely used in the production of aquatic products and considered to be a significant contributing factor to the burden of both natural and aquaculture environments. However, the main types of fluoroquinolones present in aquaculture systems have not been determined. The objectives of the present study were to explore the occurrence of residual fluoroquinolone antibiotics in fish muscle tissues sampled from across the entire aquaculture season in the Tai Lake basin in China and to assess the dietary risks associated with the upcoming vendible fish in the last month of the aquaculture season. Fluoroquinolones were detected in 95.69% of all fish samples, and the concentrations ranged from the limit of quantification (LOQ) to 47 108.00 μg · kg −1 . Enrofloxacin contributed the most among the 9 fluoroquinolone antibiotics tested. Of the 4 fish species studied, enrofloxacin was present in bream at significant ( p < 0.05) concentrations in August, with an average value of 321.45 μg · kg −1 , while enrofloxacin concentrations peaked in crab and shrimp in September, with average values of 6949.60 and 460.82 μg · kg −1 , respectively. However, different patterns were observed in perch, suggesting that other categories of antibiotics may be used in the production of this fish. Dietary risk assessment showed that the residual levels and estimated daily intake in bream, perch, and shrimp were far below the maximum residual level and acceptable daily intake. However, the average residual level in crab exceeded the maximum residual level, and the estimated daily intake value accounted for 78.49% of the acceptable daily intake, indicating potential consumption risk. In summary, the present study aims to guide the production and consumption of aquatic products. Environ Toxicol Chem 2017;36:2899–2905. © 2017 SETAC