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Exposure to the lampricide 3‐trifluoromethyl‐4‐nitrophenol results in increased expression of carbohydrate transporters in Saccharomyces cerevisiae
Author(s) -
Hinkle Karen L.,
Anderson Chad C.,
Forkey Blake,
Griffin Jacob,
Cone Kelsey,
Vitzthum Carl,
Olsen Darlene
Publication year - 2016
Publication title -
environmental toxicology and chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.1
H-Index - 171
eISSN - 1552-8618
pISSN - 0730-7268
DOI - 10.1002/etc.3314
Subject(s) - saccharomyces cerevisiae , microarray , lamprey , petromyzon , gene expression , carbohydrate , gene , biology , transporter , microarray analysis techniques , biochemistry , fishery
The lampricide 3‐trifluoromethyl‐4‐nitrophenol (TFM) is used to control sea lamprey ( Petromyzon marinus ) populations in freshwater lakes. Although TFM can have sublethal and lethal effects, little is known about gene expression changes with TFM exposure. Microarray analysis was used to determine differential gene expression over 4 h of exposure in Saccharomyces cerevisiae . Among the most significantly up‐regulated genes were regulators of carbohydrate transport, including HXT1, HXT3, HXT4, IMA5, MIG2, and YKR075C. Environ Toxicol Chem 2016;35:1727–1732. © 2015 SETAC