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Comparing the effects of nanosilver size and coating variations on bioavailability, internalization, and elimination, using Lumbriculus variegatus
Author(s) -
Coleman Jessica G.,
Kennedy Alan J.,
Bednar Anthony J.,
Ranville James F.,
Laird Jennifer G.,
Harmon Ashley R.,
Hayes Charolett A.,
Gray Evan P.,
Higgins Christopher P.,
Lotufo Guilherme,
Steevens Jeffery A.
Publication year - 2013
Publication title -
environmental toxicology and chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.1
H-Index - 171
eISSN - 1552-8618
pISSN - 0730-7268
DOI - 10.1002/etc.2278
Subject(s) - bioaccumulation , silver nanoparticle , chemistry , environmental chemistry , bioavailability , silver nitrate , particle (ecology) , particle size , inductively coupled plasma mass spectrometry , nuclear chemistry , chromatography , nanoparticle , nanotechnology , mass spectrometry , materials science , bioinformatics , biology , oceanography , geology
As the production and applications of silver nanoparticles (AgNPs) increase, it is essential to characterize fate and effects in environmental systems. Nanosilver materials may settle from suspension; therefore, the authors' objective was to utilize environmentally relevant bioassays and study the impact, bioaccumulation, tissue distribution, uptake, and depuration of AgNPs on a sediment‐dwelling invertebrate, Lumbriculus variegatus . Hydrodynamic diameters of uncoated 30‐nm, 80‐nm, and 1500‐nm AgNP powders and a polyvinyl pyrrolidone (PVP) AgNP suspension were measured utilizing dynamic light scattering in freshwater media (0–280 µS/cm). Aggregation for 30 nm, 80 nm, and 1500 nm silver increased with conductivity but was minimal for PVP silver. Lumbriculus variegatus were exposed to AgNPs or silver nitrate (AgNO 3 ) spiked into sediment (nominally 100 mg/kg) and water (PVP 30 nm and 70 nm Ag, nominally 5 mg/L). Uptake was assessed through inductively coupled plasma mass spectroscopy (ICP‐MS) and hyperspectral imaging. Particle sizes were examined through field flow fractionation–ICP‐MS (FFF‐ICP‐MS) and ICP‐MS in single particle mode (SP‐ICP‐MS). Lumbriculus variegatus were also depurated for 6 h, 8 h, 24 h, and 48 h to determine gut clearance. Bioaccumulation factors of sediment‐exposed L. variegatus were similar regardless of particle size or coatings. The FFF‐ICP‐MS and SP‐ICP‐MS detected AgNPs for up to 48 h post depuration. The present study provides information on bioaccumulation and interactions of AgNPs within biological systems. Environ Toxicol Chem 2013;32:2069–2077. © 2013 SETAC