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Comparative Effectiveness of Treatments for Binge‐Eating Disorder: Systematic Review and Network Meta‐Analysis
Author(s) -
Peat Christine M.,
Berkman Nancy D.,
Lohr Kathleen N.,
Brownley Kimberly A.,
Bann Carla M.,
Cullen Katherine,
Quattlebaum Mary J.,
Bulik Cynthia M.
Publication year - 2017
Publication title -
european eating disorders review
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.511
H-Index - 67
eISSN - 1099-0968
pISSN - 1072-4133
DOI - 10.1002/erv.2517
Subject(s) - binge eating disorder , meta analysis , eating disorders , binge eating , psychological intervention , bulimia nervosa , cinahl , abstinence , psychiatry , medline , psychology , cochrane library , strictly standardized mean difference , clinical psychology , medicine , political science , law
Psychological and pharmacological interventions for binge‐eating disorder have previously demonstrated efficacy (compared with placebo or waitlist control); thus, we aimed to expand that literature with a review of comparative effectiveness . We searched MEDLINE,® EMBASE,® Cochrane Library, Academic OneFile, CINAHL® for binge‐eating disorder treatment articles and selected studies using predetermined inclusion and exclusion criteria. Data were sufficient for network meta‐analysis comparing two pharmacological interventions; psychological interventions were analysed qualitatively. In all, 28 treatment comparisons were included in this review: one pharmacological comparison (second‐generation antidepressants versus lisdexamfetamine) and 26 psychological comparisons. Only three statistically significant differences emerged: lisdexamfetamine was better at increasing binge abstinence than second‐generation antidepressants; therapist‐led cognitive behavioural therapy was better at reducing binge‐eating frequency than behavioural weight loss, but behavioural weight loss was better at reducing weight. The majority of other treatment comparisons revealed few significant differences between groups. Thus, patients and clinicians can choose from several effective treatment options. Copyright © 2017 John Wiley & Sons, Ltd and Eating Disorders Association.