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Neurobiological and Clinical Variables Associated with Alcohol Abuse in Bulimia Nervosa
Author(s) -
VazLeal Francisco J.,
RamosFuentes María I.,
RodríguezSantos Laura,
FloresMateos Isabel S.,
FrancoZambrano Andrés,
RojoMoreno Luis,
BeatoFernández Luis
Publication year - 2015
Publication title -
european eating disorders review
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.511
H-Index - 67
eISSN - 1099-0968
pISSN - 1072-4133
DOI - 10.1002/erv.2352
Subject(s) - bulimia nervosa , impulsivity , psychology , eating disorders , borderline personality disorder , clinical psychology , psychiatry , depression (economics) , alcohol abuse , anorexia nervosa , economics , macroeconomics
The study was aimed at analysing the reciprocal relationships of several clinical and neurobiological items in order to predict alcohol misuse in patients with bulimia nervosa (BN). Seventy BN patients and 70 healthy controls were assessed for depression, impulsivity, borderline personality traits and self‐defeating behaviours using specific scales; serum cortisol and 24‐hour urinary excretion of serotonin and 5‐hydroxiindolacetic acid were also assessed. The study confirmed the implications of these clinical factors for alcohol misuse in BN patients, but the results suggested that depressive symptoms and hypercortisolism could lie behind these relationships. Copyright © 2015 John Wiley & Sons, Ltd and Eating Disorders Association.