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Associations between Liver Enzymes, Psychopathological and Clinical Features in Eating Disorders
Author(s) -
Lelli Lorenzo,
Castellini Giovanni,
Gabbani Tommaso,
Godini Lucia,
Rotella Francesco,
Ricca Valdo
Publication year - 2014
Publication title -
european eating disorders review
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.511
H-Index - 67
eISSN - 1099-0968
pISSN - 1072-4133
DOI - 10.1002/erv.2317
Subject(s) - bulimia nervosa , psychopathology , eating disorders , body mass index , overweight , medicine , anorexia nervosa , alanine aminotransferase , alanine transaminase , gastroenterology , binge eating disorder , liver enzyme , psychology , endocrinology , psychiatry
Elevated aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels are frequently reported in patients with anorexia nervosa (AN) and in subjects who are overweight or with hyperlipidemia, which can be found to be associated with binge eating disorder (BED) and bulimia nervosa (BN). Liver functioning and psychopathological features have been evaluated in 43 patients with AN, 33 with BN, and 32 with BED. Body mass index was found to be inversely associated with AST and ALT in AN, and directly associated with AST and ALT in BED. A positive association between ALT and AST and body shape concern in AN was observed. Liver enzymes could be considered as an index of severity in AN and BED patients. Copyright © 2014 John Wiley & Sons, Ltd and Eating Disorders Association.