Open AccessGenomic biomarkers in predictive medicine. An interim analysis
Author(s) -
Simon Richard
Publication year - 2011
Publication title -
embo molecular medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.923
H-Index - 107
eISSN - 1757-4684
pISSN - 1757-4676
DOI - 10.1002/emmm.201100153
Subject(s) - interim , computational biology , precision medicine , genomic medicine , medicine , bioinformatics , biology , genetics , history , archaeology
Current genomics and biotechnology promise the development of biomarkers to predict individual disease risk, enable early detection of disease, and improve diagnostic classification to better inform individualized treatment. I discuss these objectives, commenting on progress to date and obstacles to future success. The discussion mainly uses examples from oncology where the nature of the disease has expedited genomic approaches for developing biomarkers. Many of the lessons being learned in oncology, however, should be applicable to other chronic diseases.