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Does mass balance between sense and antisense transcripts fine‐tune the outcome of gene expression?
Author(s) -
YläHerttuala Seppo,
Kaikkonen Minna
Publication year - 2014
Publication title -
embo reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.584
H-Index - 184
eISSN - 1469-3178
pISSN - 1469-221X
DOI - 10.1002/embr.201338030
Subject(s) - university hospital , medicine , biology
Multiple sense and antisense non‐coding RNA transcripts are present at promoters in a sort of ‘cloud’, both enhancing and repressing expression. Is their collective effect the determining factor in the regulation of gene expression and does it help guarantee consistency across millions of cells?